S M McLachlan Selected Research

Autoimmune Diseases (Autoimmune Disease)

1/2017	High-level intrathymic thyrotrophin receptor expression in thyroiditis-prone mice protects against the spontaneous generation of pathogenic thyrotrophin receptor autoantibodies.
4/2010	Immunoglobulin heavy chain variable region genes contribute to the induction of thyroid-stimulating antibodies in recombinant inbred mice.
6/2003	Insight into antibody responses induced by plasmid or adenoviral vectors encoding thyroid peroxidase, a major thyroid autoantigen.
2/2003	Dendritic cells infected with adenovirus expressing the thyrotrophin receptor induce Graves' hyperthyroidism in BALB/c mice.
1/2000	Autoimmune response to the thyroid in humans: thyroid peroxidase--the common autoantigenic denominator.

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S M McLachlan Research Topics

Disease

9	Graves Disease (Basedow Disease) 04/2010 - 08/2000
8	Hyperthyroidism 01/2017 - 08/2001
5	Autoimmune Diseases (Autoimmune Disease) 01/2017 - 01/2000
5	Thyroiditis 01/2017 - 01/2001
2	Autoimmune Thyroiditis (Lymphomatous Thyroiditis) 01/2019 - 01/2001
1	Genetic Predisposition to Disease (Genetic Predisposition) 04/2010
1	Lymphoma (Lymphomas) 12/2004
1	Schistosomiasis mansoni 12/2004
1	Goiter 02/2003
1	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 10/2000
1	Thyroid Diseases (Thyroid Disease) 01/2000
1	Hypothyroidism 01/2000

Drug/Important Bio-Agent (IBA)

10	Thyrotropin Receptors (Thyrotropin Receptor)IBA 04/2010 - 01/2000
9	AutoantibodiesIBA 01/2017 - 01/2000
6	AntibodiesIBA 01/2019 - 11/2000
6	Thyroid-Stimulating ImmunoglobulinsIBA 04/2010 - 05/2001
5	Iodide Peroxidase (Deiodinase)IBA 01/2019 - 01/2000
4	AutoantigensIBA 01/2017 - 02/2003
3	Thyroglobulin FDA Link 01/2019 - 01/2000
3	Thyrotropin (Thyroid-Stimulating Hormone)FDA Link 01/2017 - 02/2003
3	CytokinesIBA 12/2004 - 10/2000
3	Immunoglobulin G (IgG)IBA 11/2004 - 01/2000
2	Histocompatibility Antigens Class IIIBA 06/2015 - 08/2001
2	Interferon-gamma (Interferon, gamma)IBA 12/2004 - 03/2004
2	Interleukin-4 (Interleukin 4)IBA 12/2004 - 10/2000
2	Amino Acids FDA Link 03/2004 - 05/2001
2	AntigensIBA 05/2001 - 03/2001
1	IodidesIBA 06/2015
1	Dietary SodiumIBA 06/2015
1	difluprednate FDA Link 04/2010
1	Immunoglobulin Heavy Chains (Immunoglobulin Heavy Chain)IBA 04/2010
1	alpha-galactosylceramideIBA 12/2004
1	T-Lymphocyte Epitopes (Epitopes, T Lymphocyte)IBA 03/2004
1	Peptides (Polypeptides)IBA 03/2004
1	Proteins (Proteins, Gene)FDA Link 03/2004
1	EpitopesIBA 06/2003
1	Immunodominant EpitopesIBA 06/2003
1	beta-Galactosidase (Lactaid)IBA 02/2003
1	Thyroxine (Levothyroxine)FDA LinkGeneric 02/2003
1	DNA (Deoxyribonucleic Acid)IBA 08/2001
1	laminin gamma 1IBA 05/2001
1	Epidermal Growth Factor (EGF)IBA 05/2001
1	DisulfidesIBA 05/2001
1	Biological ProductsIBA 05/2001
1	Laminin (Merosin)IBA 05/2001
1	Cysteine (L-Cysteine)FDA Link 05/2001
1	Interleukin-10 (Interleukin 10)IBA 10/2000
1	Monoclonal AntibodiesIBA 01/2000

Therapy/Procedure

2	Injections 03/2004 - 02/2003
1	Subcutaneous Injections 02/2003
1	Therapeutics 01/2000